Lactic acid bacterium Lactobacillus plantarum TENSIA® (DSM 21380)

Lactobacillus plantarum TENSIA® is a lactobacillus of human origin (isolated from a healthy Estonian child), whose safety has been tested in test tubes, laboratory animals and healthy volunteers. TENSIA® has been discovered and clinically studied by researchers at BioCC OÜ in cooperation with researchers at the University of Tartu. Lactobacillus plantarum TENSIA® has been deposited in the international microbial collection Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH under the number DSM 21380 on 16.04.2008. Lactobacillus plantarum TENSIA® belongs to BioCC OÜ and TENSIA® is a trademark of BioCC.

Properties and effects of Lactobacillus plantarum TENSIA®

L. plantarum The various properties of TENSIA® have been repeatedly studied both in the test tube (in vitro) and in animal and human experiments (in vivo).

Functional properties of L.plantarum TENSIA®:

• supplies the organism with Lactobacillus plantarum with the TENSIA® strain, which increases the body's natural resistance to several bacteria that cause intestinal infections;
• increases the total number of beneficial lactobacilli in the intestine, which ensure the breakdown of nutrients into more easily absorbed compounds;
• Produces compounds that lower blood pressure (behave similarly to NO and ACE inhibitors);
• Strengthens the body's natural defenses;
• Protects the body from excessive oxidative stress;

L. plantarum TENSIA® has been granted an Estonian patent (EE05340), a European patent (EP2309870, which has entered into force in the following countries: CY/CZ/LT/LV/PL/SE/DE/FI/GB/HU) and a Russian (RU2477750) patent: “Isolated microorganism strain Lactobacillus plantarum TENSIA® DSM 21380 as an antimicrobial and blood pressure-lowering probiotic, a foodstuff and composition containing it, and the use of a microorganism for the preparation of a blood pressure-lowering drug and a method for suppressing the action of non-starter lactobacilli in a foodstuff".

Authors: E. Songisepp, M. Mikelsaar, M. Rätsep, M. Zilmer, P. Hütt, M. Utt, K. Zilmer, J. Üksti, U. Kõljalg.

The owner of the patent is BioCC OÜ

Patents

Lactobacillus plantarum TENSIA® has won several international awards:

	Special award EWIIN 2009 At the EUWIIN (European Union Women Inventors' & Innovators' Network) conference and exhibition of women's inventions held in Helsinki in 2009, the lactic acid bacterium Lactobacillus was awarded plantarum Tensia® EUWIIN 2009 special prize.
	Gold Prize KIWIE 2009 BioCC OÜ won the gold medal at the KIWIE 2009 (Korea International Women Inventions Exposition 2009) for Lactobacillus plantarum Tensia® in Korea.
	Gold Prize KIWIE 2009 BioCC OÜ won the gold medal for Lactobacillus plantarum Tensia ® at the KIWIE 2009 (Korea International Women Inventions Exposition 2009) international inventions exhibition in Korea .
	Finnish Quality Innovation Award BioCC OÜ was awarded the 2010 Finnish Quality Innovation Award for Lactobacillus plantarum Tensia ® , which was personally presented by the President of the Republic of Finland, Mrs. Tarja Halonen (TENSIA ® properties were evaluated by independent Finnish scientific experts).

Nordwise ® products containing Lactobacillus plantarum TENSIA®

PlantaBif® N30	PlantaBif® N60
Heart Friend® TENSIA®	Ferrumar®